This information is not intended to replace the advice of your doctor. Prior to taking this or any other supplement, please consult your doctor.
Esports Healthcare disclaims any liability for the decisions you make based on this information as it does not establish, nor does it imply, doctor-patient relationship.
This is a review of Got Pain? by Skinz and not a recommendation by Esports Healthcare to purchase or use this product. These statements have not been evaluated by the Food and Drug Administration! This review is not intended to diagnose, treat, cure, or prevent any disease.
For United States residents, please review your state’s regulations on the legality of the purchase and use of CBD products as some states may have limitations. For non-US residents, please refer to your local and national regulations on CBD products prior to the purchase and use of Got Pain?
Skinz.GG (“Skinz”) is an emerging company focused on health and wellness in the gaming community. Naturally, here at Esports Healthcare, we appreciate their industry focus.
Skinz is planning to release dietary and wellness supplements to decrease pain, improve health, and support general wellness. Their first product in this line is a CBD Isolate topical cream called Got Pain?
What is CBD?
To understand CBD, you must first understand the plant from which CBD is extracted. You also need understand how the molecule works within your body.
Cannabidiol (CBD) is one chemical of the cannabis sativa plant. There are two subgroups of the cannabis plant: hemp and marijuana, and CBD exists in both. So, what’s the difference?
By definition, hemp is the subgroup of cannabis that has less than 0.3% Δ9-tetrahydrocannabinol (THC), the chemical that causes intoxication or feeling high.
At <0.3% THC, using this plant for supplements, creams, tinctures, capsules (and more) will not cause the user to feel high or intoxicated. Got Pain? is a hemp-derived CBD product with THC concentrations less than the limit of quantitation (in other words, immeasurable).
Hemp can also be used to make other products including fiber, clothing, fabric, rope, paper, a substitute for plastic, and a substitute for concrete (called “hempcrete”). However, most of the hemp farmed in the United States is cultivated for CBD products. Thus, many of these additional products are taking a back seat.
Marijuana is the subgroup of cannabis that would have >0.3% Δ9-tetrahydrocannabinol (THC), most commonly known for its psychoactive effects. THC is the portion of marijuana that causes intoxication (high).
Marijuana is still illegal in the United States under federal law. Many states have decriminalized the sale and recreational use of marijuana, but federal regulation remains.
States that have legalized recreational sale and use of marijuana include Alaska, California, Colorado, Washington DC, Illinois, Maine, Massachusetts, Michigan, Nevada, Oregon, and Vermont. In the 2020 elections, other states voted to approve legislation and will allow recreational use within the next couple years.
How does CBD work?
CBD works by enhancing molecules in your body called endocannabinoids. This name was derived following the discovery that THC from cannabis binds perfectly to specific receptor cells throughout your body.
Molecules of the cannabis plant—THC included—are called cannabinoids. Thus, the receptors were named cannabinoid receptors for their ability to receive these molecules. A later discovery was made that these receptors fit two molecules made within your body (defined as endogenous). And so, these molecules were named endocannabinoids.
These endogenous molecules and their receptors are known collectively as the endocannabinoid system (ECS). The ECS is found in nearly all organ systems of your body, and the purpose of the ECS is to maintain the homeostasis—or balance for health and well-being—of all your cells and organ systems.
CBD’s role in the endocannabinoid system
CBD does not bind directly endocannabinoid receptors. Instead, CBD enhances levels of endocannabinoids by slowing their breakdown. CBD also interacts with and enhances other neurotransmitters including serotonin, dopamine, endogenous opioids, GABA, and glutamate.
This indirect mechanism is partly why CBD does not cause intoxication or feeling high. However, by enhancing endocannabinoids and neurotransmitters, CBD plays an important role in promoting homeostasis and health of both the central and peripheral nervous systems.
Benefits of CBD
As previously mentioned, CBD plays an important role in promoting homeostasis and health of both the central and peripheral nervous systems.
Other benefits of CBD include:
- Pain reduction, particularly in the peripheral nervous system
- Systemic anti-inflammatory
- Immune support
Can CBD (Got Pain?) get you high?
No! Cannabidiol is one of many non-psychoactive molecules in cannabis. The hemp from which CBD is cultivated, by law, must contain less-than 0.3% THC, and this has been verified in Got Pain? by a third party Certificate of Analysis. Therefore, Got Pain? cannot cause consumers to feel high.
Got Pain? A CBD product for gamers
Got Pain? is a CBD isolate topical cream for the purpose of decreasing pain associated with gaming. The mechanism of action is via indirect action of the endocannabinoid system which promotes cellular and systemic homeostasis.
Since CBD prevents the breakdown of endocannabinoids, more significant benefits may be noted in areas of your body where endocannabinoids are in higher concentration.
The endocannabinoid concentration of your skin is 5-10x greater than the concentration in your brain. Thus, topical application of CBD can be highly beneficial to the endocannabinoid system in the skin and superficial layers of tissue including fascia, muscles, tendons, and nerves.
What to expect when using Got Pain?
Got Pain? has a natural, earthy scent from the herbs present in the non-active ingredients. These herbs include chamomile extract, olive leaf extract, rosemary extract, beeswax, wintergreen oil, and green tea leaf extract.
For a full list of ingredients, refer to the Got Pain? product page here. Prior to purchasing Got Pain?, check your state’s regulations regarding sale and use. Prior to using Got Pain?, consult your doctor. Additionally, you must be sure you are not allergic to any of its ingredients.
Got Pain? has a soothing sensation on your skin and is not overly greasy. However, being a product will many oils in the ingredients, Got Pain? will not leave your skin feeling completely oil-free.
Of course, as the name implies, you are most likely to experience relief of pain from common injuries and ailments experienced by gamers.
Reducing pain in common gaming injuries
The enhancement of endocannabinoids may aid in decreasing pain associated with mechanical strain (tendinopathy), nerve impingement, or tendon sheath inflammation—three common types of injuries suffered by gamers.
- Mouse elbow: a tendinopathy of the common extensor tendon, usually causing pain and discomfort on the outside (thumb side) of the elbow
- Mouse shoulder: a tendinopathy of the proximal biceps tendon, usually causing pain and discomfort on the front of the shoulder
- Medial epicondylosis: a tendinopathy of the common flexor tendon, usually causing pain and discomfort on the inside (pinky side) of the elbow
- Nerve impingement
- Cubital tunnel syndrome: a nerve impingement syndrome at the elbow, usually causing numbness, tingling, and weakness on the pinky side of the forearm and hand as well as the pinky finger and ring finger (the “funny bone” sensation)
- Carpal tunnel syndrome: a nerve impingement syndrome at the wrist, usually causing numbness, tingling, and/or weakness in the thumb side of the hand as well as the thumb, index, and middle finger
- Tendon sheath inflammation
- Gamer’s thumb: an inflammatory overuse syndrome of the tendon sheaths of the thumb, usually causing pain and discomfort on the outside (thumb side) of the wrist and forearm
For tendon sheath inflammation, Got Pain? CBD topical cream may be effective in decreasing the inflammatory process. Likewise, if nerve impingement is caused by inflammation, Got Pain? may be useful to counter that pathophysiology.
Other potential benefits of Got Pain?
Cannabinoids such as CBD may have a beneficial effect on skin tumors. Activation of the cannabinoid receptors present in the skin have been shown to modulate growth, proliferation, and differentiation of certain tumor cells, including those of both melanoma and non-melanoma.
Furthermore, CBD’s role in the endocannabinoid system may reduce the differentiation, angiogenesis (new blood vessel formation within the cancerous growth), and metastasis (spreading to another body tissue or organ system).
Got Pain? may also be useful for unbroken skin irritations such as scrapes, non-allergic irritation, or burns (including sun burn). The activation of CBD receptors can aid in the reduction of pain associated with these irritations and may play an active role in a more rapid recovery.
Note: DO NOT use Got Pain? on open skin lesions; sores; rashes, hives, or other allergic reactions; skin growths, or any other wounds. For these concerns, consult your doctor.